ageLOC LumiSpa iO conveniently and effectively cleanses away makeup, so you do not need to wash makeup off before using the device. However, some people may like to double cleanse to remove heavy makeup. In that case, you may want to use another cleanser or use your LumiSpa iO twice.
Please note that LumiSpa treatment cleansers should not be used on the eye area, so you should use a separate eye makeup remover to remove makeup on and around the eyes.